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Intracellular calcium dependence of gene expression in single T lymphocytes.

In T lymphocytes, intracellular Ca2+ concentration ([Ca2+]i) rises within seconds of T-cell antigen-receptor stimulation and initiates the synthesis and secretion of interleukin 2, a cytokine essential for T-cell proliferation and the immune response. Using video-imaging techniques, we tracked [Ca2+...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Negulescu, P A, Shastri, N, Cahalan, M D
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1994
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43473/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8146203/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.7.2873
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