The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive form of leukemia that is mainly diagnosed in children and shows a skewed gender distribution toward males. In this study, we report somatic loss-of-function mutations in the X-linked histone H3K27me3 demethylase ubiquitously transcribed X...

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Xehetasun bibliografikoak
Argitaratua izan da:Blood
Egile Nagusiak: Van der Meulen, Joni, Sanghvi, Viraj, Mavrakis, Konstantinos, Durinck, Kaat, Fang, Fang, Matthijssens, Filip, Rondou, Pieter, Rosen, Monica, Pieters, Tim, Vandenberghe, Peter, Delabesse, Eric, Lammens, Tim, De Moerloose, Barbara, Menten, Björn, Van Roy, Nadine, Verhasselt, Bruno, Poppe, Bruce, Benoit, Yves, Taghon, Tom, Melnick, Ari M., Speleman, Frank, Wendel, Hans-Guido, Van Vlierberghe, Pieter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2015
Gaiak:
Plenary Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347284/
https://ncbi.nlm.nih.gov/pubmed/25320243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-05-577270
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