VEGF-C and aortic cardiomyocytes guide coronary artery stem development

Coronary arteries (CAs) stem from the aorta at 2 highly stereotyped locations, deviations from which can cause myocardial ischemia and death. CA stems form during embryogenesis when peritruncal blood vessels encircle the cardiac outflow tract and invade the aorta, but the underlying patterning mecha...

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Vydáno v:J Clin Invest
Hlavní autoři: Chen, Heidi I., Poduri, Aruna, Numi, Harri, Kivela, Riikka, Saharinen, Pipsa, McKay, Andrew S., Raftrey, Brian, Churko, Jared, Tian, Xueying, Zhou, Bin, Wu, Joseph C., Alitalo, Kari, Red-Horse, Kristy
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347240/
https://ncbi.nlm.nih.gov/pubmed/25271623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77483
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