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Engrafted human stem cell–derived hepatocytes establish an infectious HCV murine model

The demonstrated ability to differentiate both human embryonic stem cells (hESCs) and patient-derived induced pluripotent stem cells (hiPSCs) into hepatocyte-like cells (HLCs) holds great promise for both regenerative medicine and liver disease research. Here, we determined that, despite an immature...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Carpentier, Arnaud, Tesfaye, Abeba, Chu, Virginia, Nimgaonkar, Ila, Zhang, Fang, Lee, Seung Bum, Thorgeirsson, Snorri S., Feinstone, Stephen M., Liang, T. Jake
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347235/
https://ncbi.nlm.nih.gov/pubmed/25295540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75456
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