Prostanoid induces premetastatic niche in regional lymph nodes

The lymphatic system is an important route for cancer dissemination, and lymph node metastasis (LNM) serves as a critical prognostic determinant in cancer patients. We investigated the contribution of COX-2–derived prostaglandin E(2) (PGE(2)) in the formation of a premetastatic niche and LNM. A muri...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Ogawa, Fumihiro, Amano, Hideki, Eshima, Koji, Ito, Yoshiya, Matsui, Yoshio, Hosono, Kanako, Kitasato, Hidero, Iyoda, Akira, Iwabuchi, Kazuya, Kumagai, Yuji, Satoh, Yukitoshi, Narumiya, Shuh, Majima, Masataka
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347225/
https://ncbi.nlm.nih.gov/pubmed/25271626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73530
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