Quantitative Expression Analysis of APP Pathway and Tau Phosphorylation-Related Genes in the ICV STZ-Induced Non-Human Primate Model of Sporadic Alzheimer’s Disease

The accumulation and aggregation of misfolded proteins in the brain, such as amyloid-β (Aβ) and hyperphosphorylated tau, is a neuropathological hallmark of Alzheimer’s disease (AD). Previously, we developed and validated a novel non-human primate model for sporadic AD (sAD) research using intracereb...

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Udgivet i:Int J Mol Sci
Main Authors: Park, Sang-Je, Kim, Young-Hyun, Nam, Gyu-Hwi, Choe, Se-Hee, Lee, Sang-Rae, Kim, Sun-Uk, Kim, Ji-Su, Sim, Bo-Woong, Song, Bong-Seok, Jeong, Kang-Jin, Lee, Youngjeon, Park, Young Il, Lee, Kyoung-Min, Huh, Jae-Won, Chang, Kyu-Tae
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346842/
https://ncbi.nlm.nih.gov/pubmed/25622254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16022386
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