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Brain ACE2 overexpression reduces DOCA-salt hypertension independently of endoplasmic reticulum stress

Endoplasmic reticulum (ER) stress was previously reported to contribute to neurogenic hypertension while neuronal angiotensin-converting enzyme type 2 (ACE2) overexpression blunts the disease. To assess which brain regions are important for ACE2 beneficial effects and the contribution of ER stress t...

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Veröffentlicht in:Am J Physiol Regul Integr Comp Physiol
Hauptverfasser: Xia, Huijing, de Queiroz, Thyago Moreira, Sriramula, Srinivas, Feng, Yumei, Johnson, Tanya, Mungrue, Imran N., Lazartigues, Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346759/
https://ncbi.nlm.nih.gov/pubmed/25519733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00366.2014
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