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A skin microRNA promotes differentiation by repressing ‘stemness’

In stratified epithelial tissues, homeostasis relies on the self-renewing capacity of stem cells located within the innermost basal layer1. As basal cells become suprabasal, they lose proliferative potential and embark on a terminal differentiation programme2,3. Here, we show that microRNA-203 is in...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Yi, Rui, Poy, Matthew N., Stoffel, Markus, Fuchs, Elaine
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346711/
https://ncbi.nlm.nih.gov/pubmed/18311128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06642
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