High Enantioselective Novozym 435-Catalyzed Esterification of (R,S)-Flurbiprofen Monitored with a Chiral Stationary Phase

Lipases form Candida rugosa and Candida antarctica were tested for their application in the enzymatic kinetic resolution of (R,S)-flurbiprofen by enantioselective esterification. Successful chromatographic separation with well-resolved peaks of (R)- and (S)-flurbiprofen and their esters was achieved...

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Bibliografiske detaljer
Udgivet i:Appl Biochem Biotechnol
Main Authors: Siódmiak, Tomasz, Mangelings, Debby, Heyden, Yvan Vander, Ziegler-Borowska, Marta, Marszałł, Michał Piotr
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346682/
https://ncbi.nlm.nih.gov/pubmed/25561056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12010-014-1455-4
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