Effect of Inhaled Endotoxin on Mucociliary Clearance and Airway Inflammation in Mild Smokers and Nonsmokers

Background: In healthy nonsmokers, inhaled endotoxin [lipopolysaccharide (LPS)] challenge induces airway neutrophilia and modifies innate immune responses, but the effect on mucociliary clearance (MCC), a key host defense response, is unknown. Although smokers are chronically exposed to LPS through...

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Bibliografiske detaljer
Udgivet i:J Aerosol Med Pulm Drug Deliv
Main Authors: Bennett, William D., Alexis, Neil E., Almond, Martha, Herbst, Margaret, Zeman, Kirby L., Peden, David B.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2014
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346607/
https://ncbi.nlm.nih.gov/pubmed/24568613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jamp.2013.1089
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