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Preparation and In Vitro Evaluation of Hydrophilic Fenretinide Nanoparticles

Fenretinide is an effective anti-cancer drug with high in vitro cytotoxicity and low in vivo systemic toxicity. In clinical trials, fenretinide has shown poor therapeutic efficacy following oral administration – attributed to its low bioavailability and solubility. The long term goal of this project...

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Detalhes bibliográficos
Publicado no:Int J Pharm
Main Authors: Ledet, Grace A., Graves, Richard A., Glotser, Elena Y., Mandal, Tarun K., Bostanian, Levon A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346548/
https://ncbi.nlm.nih.gov/pubmed/25542987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2014.12.052
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