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Effect of antidepressant drugs on the vmPFC-limbic circuitry

Our recent study indicates that the lesions of the prefrontal cortex in rats result in depressive-like behavior in forced swim test and REM sleep alterations, two well-established biomarkers of depression disorder. We hypothesized that antidepressants may target the PFC to reverse depression. System...

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Bibliographic Details
Published in:Neuropharmacology
Main Authors: Chang, Celene H., Chen, Michael C, Lu, Jun
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346479/
https://ncbi.nlm.nih.gov/pubmed/25637091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.01.010
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