ATF3 Protects Pulmonary Resident Cells from Acute and Ventilator-Induced Lung Injury by Preventing Nrf2 Degradation

Aims: Ventilator-induced lung injury (VILI) contributes to mortality in patients with acute respiratory distress syndrome, the most severe form of acute lung injury (ALI). Absence of activating transcription factor 3 (ATF3) confers susceptibility to ALI/VILI. To identify cell-specific ATF3-dependent...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Shan, Yuexin, Akram, Ali, Amatullah, Hajera, Zhou, Dun Yuan, Gali, Patricia L., Maron-Gutierrez, Tatiana, González-López, Adrian, Zhou, Louis, Rocco, Patricia R.M., Hwang, David, Albaiceta, Guillermo M., Haitsma, Jack J., dos Santos, Claudia C.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Original Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346377/
https://ncbi.nlm.nih.gov/pubmed/25401197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2014.5987
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