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Improvement of memory deficits and Aβ clearance in aged APP23 mice treated with a combination of anti-Aβ antibody and LXR agonist
Passive Aβ vaccination has shown significant effects on amyloid pathology in pre-depositing APP mice but the results in older mice are inconsistent. A therapeutic effect of LXR and RXR agonists consisting of improved memory deficits and Aβ pathology has been demonstrated in different AD mouse models...
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| Publié dans: | J Alzheimers Dis |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4346309/ https://ncbi.nlm.nih.gov/pubmed/24643138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-132789 |
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