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Prospective Study in a Porcine Model of Sarcoptes scabiei Indicates the Association of Th2 and Th17 Pathways with the Clinical Severity of Scabies

BACKGROUND: Understanding of scabies immunopathology has been hampered by the inability to undertake longitudinal studies in humans. Pigs are a useful animal model for scabies, and show clinical and immunologic changes similar to those in humans. Crusted scabies can be readily established in pigs by...

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Publicat a:PLoS Negl Trop Dis
Autors principals: Mounsey, Kate E., Murray, Hugh C., Bielefeldt-Ohmann, Helle, Pasay, Cielo, Holt, Deborah C., Currie, Bart J., Walton, Shelley F., McCarthy, James S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346266/
https://ncbi.nlm.nih.gov/pubmed/25730203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003498
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