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Hematopoietic stem cell arrival triggers dynamic remodeling of the perivascular niche

Hematopoietic stem and progenitor cells (HSPCs) can reconstitute and sustain the entire blood system. We generated a highly specific transgenic reporter of HSPCs in zebrafish. This allowed us to perform high-resolution live imaging on endogenous HSPCs not currently possible in mammalian bone marrow....

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Foilsithe in:Cell
Main Authors: Tamplin, Owen J., Durand, Ellen M., Carr, Logan A., Childs, Sarah J., Hagedorn, Elliott J., Li, Pulin, Yzaguirre, Amanda D., Speck, Nancy A., Zon, Leonard I.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346256/
https://ncbi.nlm.nih.gov/pubmed/25594182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.12.032
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