Role of S-nitrosoglutathione mediated mechanisms in Tau Hyper-phosphorylation

Hyperphosphorylation and polymerization of microtubule-associated protein tau into paired helical filaments (PHFs) is one of the hallmarks of Alzheimer’s disease (AD). Here we report that neuronal tau hyperphosphorylation under AD conditions is regulated by Snitrosoglutathione (GSNO), an endogenous...

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Bibliografiset tiedot
Julkaisussa:Biochem Biophys Res Commun
Päätekijät: Annamalai, Balasubramaniam, Won, Je-Seong, Choi, Seungho, Singh, Inderjit, Singh, Avtar K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346186/
https://ncbi.nlm.nih.gov/pubmed/25640839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.01.093
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