Tetrahydrobiopterin and alkylglycerol monooxygenase substantially alter the murine macrophage lipidome

Tetrahydrobiopterin is a cofactor synthesized from GTP with well-known roles in enzymatic nitric oxide synthesis and aromatic amino acid hydroxylation. It is used to treat mild forms of phenylketonuria. Less is known about the role of tetrahydrobiopterin in lipid metabolism, although it is essential...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Watschinger, Katrin, Keller, Markus A., McNeill, Eileen, Alam, Mohammad T., Lai, Steven, Sailer, Sabrina, Rauch, Veronika, Patel, Jyoti, Hermetter, Albin, Golderer, Georg, Geley, Stephan, Werner-Felmayer, Gabriele, Plumb, Robert S., Astarita, Giuseppe, Ralser, Markus, Channon, Keith M., Werner, Ernst R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2015
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345615/
https://ncbi.nlm.nih.gov/pubmed/25675482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414887112
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