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Neuroinflammation triggered by β-glucan/dectin-1 signaling enables CNS axon regeneration

Innate immunity can facilitate nervous system regeneration, yet the underlying cellular and molecular mechanisms are not well understood. Here we show that intraocular injection of lipopolysaccharide (LPS), a bacterial cell wall component, or the fungal cell wall extract zymosan both lead to rapid a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Baldwin, Katherine T., Carbajal, Kevin S., Segal, Benjamin M., Giger, Roman J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345569/
https://ncbi.nlm.nih.gov/pubmed/25675510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423221112
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