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Roles of nicotinic acetylcholine receptor β subunit cytoplasmic loops in acute desensitization and single channel features

To evaluate physiological roles of the large, second cytoplasmic loops (C2) situated between the M3 and M4 transmembrane domains of nicotinic acetylcholine receptor (nAChR) subunits. We have constructed chimeric β2 (β2χ) and β4 (β4χ) subunits in which the “nested” C2 domains (but not the “proximal”...

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Bibliografiske detaljer
Udgivet i:Neuroscience
Main Authors: Liu, Qiang, Kuo, Yen-Ping, Shen, Jianxin, Lukas, Ronald J., Wu, Jie
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344923/
https://ncbi.nlm.nih.gov/pubmed/25536046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.12.016
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