Early steps in primary cilium assembly require EHD1- and EHD3-dependent ciliary vesicle formation

Membrane association with mother centriole (M-centriole) distal appendages is critical for ciliogenesis initiation. How the Rab GTPase Rab11-Rab8 cascade functions in early ciliary membrane assembly is unknown. Here, we show that the membrane shaping proteins EHD1 and EHD3, in association with the R...

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Publicat a:Nat Cell Biol
Autors principals: Lu, Quanlong, Insinna, Christine, Ott, Carolyn, Stauffer, Jimmy, Pintado, Petra A., Rahajeng, Juliati, Baxa, Ulrich, Walia, Vijay, Cuenca, Adrian, Hwang, Yoo-Seok, Daar, Ira O., Lopes, Susana, Lippincott-Schwartz, Jennifer, Jackson, Peter K., Caplan, Steve, Westlake, Christopher J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344897/
https://ncbi.nlm.nih.gov/pubmed/25686250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3109
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