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Integrated allosteric regulation in the S. cerevisiae carbamylphosphate synthetase – aspartate transcarbamylase multifunctional protein

BACKGROUND: The S. cerevisiae carbamylphosphate synthetase – aspartate transcarbamylase multifunctional protein catalyses the first two reactions of the pyrimidine pathway. In this organism, these two reactions are feedback inhibited by the end product UTP. In the present work, the mechanisms of the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Serre, Valérie, Penverne, Bernadette, Souciet, Jean-Luc, Potier, Serge, Guy, Hedeel, Evans, David, Vicart, Patrick, Hervé, Guy
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC434488/
https://ncbi.nlm.nih.gov/pubmed/15128434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-5-6
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