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Integrated allosteric regulation in the S. cerevisiae carbamylphosphate synthetase – aspartate transcarbamylase multifunctional protein

BACKGROUND: The S. cerevisiae carbamylphosphate synthetase – aspartate transcarbamylase multifunctional protein catalyses the first two reactions of the pyrimidine pathway. In this organism, these two reactions are feedback inhibited by the end product UTP. In the present work, the mechanisms of the...

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Detalhes bibliográficos
Main Authors: Serre, Valérie, Penverne, Bernadette, Souciet, Jean-Luc, Potier, Serge, Guy, Hedeel, Evans, David, Vicart, Patrick, Hervé, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC434488/
https://ncbi.nlm.nih.gov/pubmed/15128434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-5-6
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