Integrated allosteric regulation in the S. cerevisiae carbamylphosphate synthetase – aspartate transcarbamylase multifunctional protein

BACKGROUND: The S. cerevisiae carbamylphosphate synthetase – aspartate transcarbamylase multifunctional protein catalyses the first two reactions of the pyrimidine pathway. In this organism, these two reactions are feedback inhibited by the end product UTP. In the present work, the mechanisms of the...

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Bibliographic Details
Main Authors: Serre, Valérie, Penverne, Bernadette, Souciet, Jean-Luc, Potier, Serge, Guy, Hedeel, Evans, David, Vicart, Patrick, Hervé, Guy
Format: Artigo
Language:Inglês
Published: BioMed Central 2004
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC434488/
https://ncbi.nlm.nih.gov/pubmed/15128434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-5-6
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