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The Anti-Cancer Potency and Mechanism of a Novel Tumor-Activated Fused Toxin, DLM

Melittin, which acts as a membrane-disrupting lytic peptide, is not only cytotoxic to tumors, but also vital to normal cells. Melittin had low toxicity when coupled with target peptides. Despite significant research development with the fused toxin, a new fused toxin is needed which has a cleavable...

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Bibliografske podrobnosti
izdano v:Toxins (Basel)
Main Authors: Sun, Dejun, Sun, Miaonan, Zhu, Wenhe, Wang, Zhiding, Li, Yuefei, Ma, Jie
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344633/
https://ncbi.nlm.nih.gov/pubmed/25658509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins7020423
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