STAMP: Sequence tag-based analysis of microbial population dynamics

We describe a new method (STAMP) for characterization of pathogen population dynamics during infection. STAMP analyzes the frequency changes of genetically “barcoded” organisms to quantify population bottlenecks and infer the founding population size. Analyses of intra-intestinal Vibrio cholerae rev...

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Bibliographic Details
Published in:Nat Methods
Main Authors: Abel, Sören, zur Wiesch, Pia Abel, Chang, Hsiao-Han, Davis, Brigid M., Lipsitch, Marc, Waldor, Matthew K.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344388/
https://ncbi.nlm.nih.gov/pubmed/25599549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3253
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