Association of Brain DNA Methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 With Pathological Diagnosis of Alzheimer Disease

IMPORTANCE: Recent large-scale genome-wide association studies have discovered several genetic variants associated with Alzheimer disease (AD); however, the extent to which DNA methylation in these AD loci contributes to the disease susceptibility remains unknown. OBJECTIVE: To examine the associati...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Yu, Lei, Chibnik, Lori B., Srivastava, Gyan P., Pochet, Nathalie, Yang, Jingyun, Xu, Jishu, Kozubek, James, Obholzer, Nikolaus, Leurgans, Sue E., Schneider, Julie A., Meissner, Alexander, De Jager, Philip L., Bennett, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344367/
https://ncbi.nlm.nih.gov/pubmed/25365775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2014.3049
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