Conformational Changes in a Hyperthermostable Glycoside Hydrolase: Enzymatic Activity Is a Consequence of the Loop Dynamics and Protonation Balance

Endo-β-1, 4-mannanase from Thermotoga petrophila (TpMan) is a modular hyperthermostable enzyme involved in the degradation of mannan-containing polysaccharides. The degradation of these polysaccharides represents a key step for several industrial applications. Here, as part of a continuing investiga...

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Vydáno v:PLoS One
Hlavní autoři: de Oliveira, Leandro C., da Silva, Viviam M., Colussi, Francieli, Cabral, Aline D., de Oliveira Neto, Mario, Squina, Fabio M., Garcia, Wanius
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344334/
https://ncbi.nlm.nih.gov/pubmed/25723179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118225
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