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A multimeric MR-optical contrast agent for multimodal imaging()

We describe the design, synthesis and in vitro evaluation of a multimodal and multimeric contrast agent. The agent consists of three macrocyclic Gd(III) chelates conjugated to a fluorophore and possesses high relaxivity, water solubility, and is nontoxic. The modular synthesis is amenable for the in...

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Bibliographic Details
Published in:Chem Commun (Camb)
Main Authors: Harrison, Victoria S. R., Carney, Christiane E., Macrenaris, Keith W., Meade, Thomas J.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344311/
https://ncbi.nlm.nih.gov/pubmed/25137290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc05651e
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