Reduced expression of the presynaptic co-chaperone cysteine string protein alpha (CSPα) does not exacerbate experimentally-induced ME7 prion disease

Infection of mice with the ME7 prion agent results in well-characterised neuropathological changes, which includes vacuolation, neurodegeneration and synaptic degeneration. Presynaptic dysfunction and degeneration is apparent through the progressive reduction in synaptic vesicle proteins and eventua...

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Detalhes bibliográficos
Publicado no:Neurosci Lett
Main Authors: Davies, Matthew J., Cooper, Matthew, Perry, V. Hugh, O’Connor, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Scientific Publishers Ireland 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344215/
https://ncbi.nlm.nih.gov/pubmed/25623034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2015.01.053
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