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Cloning and analysis of the Saccharomyces cerevisiae MNN9 and MNN1 genes required for complex glycosylation of secreted proteins.

Proteins secreted by the yeast Saccharomyces cerevisiae are usually modified by the addition at asparagine-linked glycosylation sites of large heterogeneous mannan units that are highly immunogenic. Secreted proteins from mnn1 mnn9 mutant strains, in contrast, have homogeneous Man10GlcNAc2 oligosacc...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Yip, C L, Welch, S K, Klebl, F, Gilbert, T, Seidel, P, Grant, F J, O'Hara, P J, MacKay, V L
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1994
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43442/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8146181/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.7.2723
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