Laddar...
A constitutively active mutant beta 2-adrenergic receptor is constitutively desensitized and phosphorylated.
The beta 2-adrenergic receptor (beta 2AR) can be constitutively activated by mutations in the third intracellular loop. Whereas the wild-type receptor exists predominantly in an inactive conformation (R) in the absence of agonist, the mutant receptor appears to spontaneously adopt an active conforma...
Sparad:
| Huvudupphovsmän: | , , , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
1994
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC43437/ https://ncbi.nlm.nih.gov/pubmed/7908440 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|