Vitamin D: Concerning the Relationship Between Molecular Topology and Biological Function

Structure-function relationships for vitamin D, its metabolites, and analogs are discussed with particular emphasis on the A-ring conformation. It is emphasized that the A-ring of these seco-steroids consists of a pair of rapidly equilibrating chair conformers. As a consequence, different chair conf...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Okamura, William H., Norman, Anthony W., Wing, Richard M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1974
Assuntos:	Biological Sciences: Biochemistry
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434356/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4372612/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.10.4194
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