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Structural basis for transcription reactivation by RapA

RNA polymerase (RNAP) loses activity during transcription as it stalls at various inactive states due to erratic translocation. Reactivation of these stalled RNAPs is essential for efficient RNA synthesis. Here we report a 4.7-Å resolution crystal structure of the Escherichia coli RNAP core enzyme i...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Liu, Bin, Zuo, Yuhong, Steitz, Thomas A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343176/
https://ncbi.nlm.nih.gov/pubmed/25646438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417152112
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