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JMJD3 promotes chondrocyte proliferation and hypertrophy during endochondral bone formation in mice

JMJD3 (KDM6B) is an H3K27me3 demethylase and counteracts polycomb-mediated transcription repression. However, the function of JMJD3 in vivo is not well understood. Here we show that JMJD3 is highly expressed in cells of the chondrocyte lineage, especially in prehypertrophic and hypertrophic chondroc...

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書目詳細資料
發表在:J Mol Cell Biol
Main Authors: Zhang, Feng, Xu, Longyong, Xu, Longxia, Xu, Qing, Li, Dangsheng, Yang, Yingzi, Karsenty, Gerard, Chen, Charlie Degui
格式: Artigo
語言:Inglês
出版: Oxford University Press 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342687/
https://ncbi.nlm.nih.gov/pubmed/25587042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjv003
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