Differentiation-Induced Radioresistance in Muscle Cells

DNA damage induces cell cycle arrest and DNA repair or apoptosis in proliferating cells. Terminally differentiated cells are permanently withdrawn from the cell cycle and partly resistant to apoptosis. To investigate the effects of genotoxic agents in postmitotic cells, we compared DNA damage-activa...

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Bibliographic Details
Main Authors: Latella, Lucia, Lukas, Jiri, Simone, Cristiano, Puri, Pier Lorenzo, Bartek, Jiri
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC434249/
https://ncbi.nlm.nih.gov/pubmed/15226436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.14.6350-6361.2004
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