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β(2)-Glycoprotein I-specific T Cells Are Associated with Epitope Spread to Lupus-related Autoantibodies

Systemic lupus erythematosus (SLE) is a prototypic model for B cell epitope spread in autoimmunity. Autoantibodies to numerous and molecularly distinct self-antigens emerge in a sequential manner over several years, leading to disease manifestations. Among the earliest autoantibodies to appear are t...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Salem, David, Subang, Rebecca, Okazaki, Yuka, Laplante, Patrick, Levine, Jerrold S., Kuwana, Masataka, Rauch, Joyce
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342469/
https://ncbi.nlm.nih.gov/pubmed/25555913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.619817
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