Crystal Structures Capture Three States in the Catalytic Cycle of a Pyridoxal Phosphate (PLP) Synthase

PLP synthase (PLPS) is a remarkable single-enzyme biosynthetic pathway that produces pyridoxal 5′-phosphate (PLP) from glutamine, ribose 5-phosphate, and glyceraldehyde 3-phosphate. The intact enzyme includes 12 synthase and 12 glutaminase subunits. PLP synthesis occurs in the synthase active site b...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Smith, Amber Marie, Brown, William Clay, Harms, Etti, Smith, Janet L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Protein Structure and Folding
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342443/
https://ncbi.nlm.nih.gov/pubmed/25568319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.626382
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares