Global Nature of Dynamic Protein-Chromatin Interactions In Vivo: Three-Dimensional Genome Scanning and Dynamic Interaction Networks of Chromatin Proteins

Genome structure and gene expression depend on a multitude of chromatin-binding proteins. The binding properties of these proteins to native chromatin in intact cells are largely unknown. Here, we describe an approach based on combined in vivo photobleaching microscopy and kinetic modeling to analyz...

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Bibliographic Details
Main Authors: Phair, Robert D., Scaffidi, Paola, Elbi, Cem, Vecerová, Jaromíra, Dey, Anup, Ozato, Keiko, Brown, David T., Hager, Gordon, Bustin, Michael, Misteli, Tom
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC434243/
https://ncbi.nlm.nih.gov/pubmed/15226439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.14.6393-6402.2004
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