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Ribosomopathies and the paradox of cellular hypo- to hyperproliferation

Ribosomopathies are largely congenital diseases linked to defects in ribosomal proteins or biogenesis factors. Some of these disorders are characterized by hypoproliferative phenotypes such as bone marrow failure and anemia early in life, followed by elevated cancer risks later in life. This transit...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: De Keersmaecker, Kim, Sulima, Sergey O., Dinman, Jonathan D.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342353/
https://ncbi.nlm.nih.gov/pubmed/25575543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-569616
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