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Ribosomopathies and the paradox of cellular hypo- to hyperproliferation

Ribosomopathies are largely congenital diseases linked to defects in ribosomal proteins or biogenesis factors. Some of these disorders are characterized by hypoproliferative phenotypes such as bone marrow failure and anemia early in life, followed by elevated cancer risks later in life. This transit...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: De Keersmaecker, Kim, Sulima, Sergey O., Dinman, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342353/
https://ncbi.nlm.nih.gov/pubmed/25575543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-10-569616
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