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Deficiency of Brain ABCA1 Exacerbates Blood Brain Barrier and White Matter Damage after Stroke
BACKGROUND AND PURPOSE: The ATP-binding cassette transporter A-1 (ABCA1) gene is a key target of the transcription factors liver-X-receptors (LXRs). LXR activation has anti-inflammatory and neuroprotective effects in animal ischemic stroke models. Here, we tested the hypothesis that brain ABCA1 redu...
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| Publicado no: | Stroke |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4342295/ https://ncbi.nlm.nih.gov/pubmed/25593138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.114.007145 |
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