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New Genes that Extend C. elegans’ Lifespan in Response to Reproductive Signals

In C. elegans and Drosophila, removing germline stem cells increases lifespan. In C. elegans, this lifespan extension requires DAF-16, a FOXO transcription factor and DAF-12, a nuclear hormone receptor. To better understand the regulatory relationships between DAF-16 and DAF-12, we used microarray a...

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Bibliografische gegevens
Gepubliceerd in:Aging Cell
Hoofdauteurs: McCormick, Mark, Chen, Kan, Ramaswamy, Priya, Kenyon, Cynthia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342234/
https://ncbi.nlm.nih.gov/pubmed/22081913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00768.x
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