Extra Copies of the Aspergillus fumigatus Squalene Epoxidase Gene Confer Resistance to Terbinafine: Genetic Approach to Studying Gene Dose-Dependent Resistance to Antifungals in A. fumigatus

With the increasing use of antifungals such as amphotericin B, itraconazole, voriconazole, caspofungin, and terbinafine (TRB) in patients at high risk for invasive aspergillosis, resistance of Aspergillus fumigatus to these agents will ultimately emerge. Due to the limited availability of molecular...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Liu, Wei, May, Gregory S., Lionakis, Michail S., Lewis, Russell E., Kontoyiannis, Dimitrios P.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2004
विषय:
Mechanisms of Resistance
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC434218/
https://ncbi.nlm.nih.gov/pubmed/15215099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.7.2490-2496.2004
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