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Blockade of specific Notch ligands: A new promising approach in cancer therapy

The signaling specificity conveyed by distinct combination of Notch receptors/ligands has remained elusive. In this issue of Cancer Discovery, through the development of ligand-specific Notch inhibitors, Kangsamaksin et al. uncovered unique signaling outcomes downstream of DLL- and JAG- receptor act...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Briot, Anaïs, Iruela-Arispe, M. Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342039/
https://ncbi.nlm.nih.gov/pubmed/25656896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-14-1501
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