TRAF2 recruitment via T61 in CD30 drives NFκB activation and enhances hESC survival and proliferation

CD30 (TNFRSF8), a tumor necrosis factor receptor family protein, and CD30 variant (CD30v), a ligand-independent form encoding only the cytoplasmic signaling domain, are concurrently overexpressed in transformed human embryonic stem cells (hESCs) or hESCs cultured in the presence of ascorbate. CD30 a...

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Bibliographic Details
Published in:Mol Biol Cell
Main Authors: Thakar, Nilay Y., Ovchinnikov, Dmitry A., Hastie, Marcus L., Kobe, Bostjan, Gorman, Jeffrey J., Wolvetang, Ernst J.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2015
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342033/
https://ncbi.nlm.nih.gov/pubmed/25568342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-08-1290
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