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Rab31 and APPL2 enhance FcγR-mediated phagocytosis through PI3K/Akt signaling in macrophages

Membrane remodeling in the early stages of phagocytosis enables the engulfment of particles or pathogens and receptor signaling to activate innate immune responses. Members of the Rab GTPase family and their disparate effectors are recruited sequentially to regulate steps throughout phagocytosis. Ra...

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Pubblicato in:Mol Biol Cell
Autori principali: Yeo, Jeremy C., Wall, Adam A., Luo, Lin, Stow, Jennifer L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342030/
https://ncbi.nlm.nih.gov/pubmed/25568335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-10-1457
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