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Optimization of the heme biosynthesis pathway for the production of 5-aminolevulinic acid in Escherichia coli
5-Aminolevulinic acid (ALA), the committed intermediate of the heme biosynthesis pathway, shows significant promise for cancer treatment. Here, we identified that in addition to hemA and hemL, hemB, hemD, hemF, hemG and hemH are also the major regulatory targets of the heme biosynthesis pathway. Int...
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| Vydáno v: | Sci Rep |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4341193/ https://ncbi.nlm.nih.gov/pubmed/25716896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08584 |
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