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E1B-55-Kilodalton Protein Is Not Required To Block p53-Induced Transcription during Adenovirus Infection

The adenovirus E1B-55-kDa protein binds and inactivates the tumor suppressor protein p53. However, the role of this interaction during infection is still poorly understood and was therefore examined here. Infection with a virus carrying the E1B-55-kDa mutation R239A, preventing the interaction with...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Hobom, Urs, Dobbelstein, Matthias
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434109/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15220443/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.14.7685-7697.2004
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