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Enhanced Neurite Outgrowth of Human Model (NT2) Neurons by Small-Molecule Inhibitors of Rho/ROCK Signaling

Axonal injury in the adult human central nervous system often results in loss of sensation and motor functions. Promoting regeneration of severed axons requires the inactivation of growth inhibitory influences from the tissue environment and stimulation of the neuron intrinsic growth potential. Espe...

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Pubblicato in:PLoS One
Autori principali: Roloff, Frank, Scheiblich, Hannah, Dewitz, Carola, Dempewolf, Silke, Stern, Michael, Bicker, Gerd
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340918/
https://ncbi.nlm.nih.gov/pubmed/25714396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118536
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