Protective Immunogenicity of Group A Streptococcal M-Related Proteins

Many previous studies have focused on the surface M proteins of group A streptococci (GAS) as virulence determinants and protective antigens. However, the majority of GAS isolates express M-related protein (Mrp) in addition to M protein, and both have been shown to be required for optimal virulence....

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Bibliographic Details
Published in:Clin Vaccine Immunol
Main Authors: Dale, James B., Niedermeyer, Shannon E., Agbaosi, Tina, Hysmith, Nicholas D., Penfound, Thomas A., Hohn, Claudia M., Pullen, Matthew, Bright, Michael I., Murrell, Daniel S., Shenep, Lori E., Courtney, Harry S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340887/
https://ncbi.nlm.nih.gov/pubmed/25630406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00795-14
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