Protective Immunogenicity of Group A Streptococcal M-Related Proteins

Many previous studies have focused on the surface M proteins of group A streptococci (GAS) as virulence determinants and protective antigens. However, the majority of GAS isolates express M-related protein (Mrp) in addition to M protein, and both have been shown to be required for optimal virulence....

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Bibliographische Detailangaben
Veröffentlicht in:Clin Vaccine Immunol
Hauptverfasser: Dale, James B., Niedermeyer, Shannon E., Agbaosi, Tina, Hysmith, Nicholas D., Penfound, Thomas A., Hohn, Claudia M., Pullen, Matthew, Bright, Michael I., Murrell, Daniel S., Shenep, Lori E., Courtney, Harry S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340887/
https://ncbi.nlm.nih.gov/pubmed/25630406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00795-14
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