Integrin Mediated Adhesion of Osteoblasts to Connective Tissue Growth Factor (CTGF/CCN2) Induces Cytoskeleton Reorganization and Cell Differentiation

Pre-osteoblast adhesion and interaction with extracellular matrix (ECM) proteins through integrin receptors result in activation of signaling pathways regulating osteoblast differentiation. Connective tissue growth factor (CTGF/CCN2) is a matricellular protein secreted into the ECM. Prior studies in...

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Bibliographic Details
Published in:PLoS One
Main Authors: Hendesi, Honey, Barbe, Mary F., Safadi, Fayez F., Monroy, M. Alexandra, Popoff, Steven N.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340870/
https://ncbi.nlm.nih.gov/pubmed/25714841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115325
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